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These effects were potentiated by sildenafil. In a recent study we identified the molecular players of cGMP signaling in murine and human melanoma cells. C-type natriuretic peptide CNP a horney goat weed with viagra of the membrane-bound guanylate cyclase B GC-B strongly increased intracellular cGMP concentrations and the activity of cGMP-dependent protein kinase I PRKG1, also known as PKG or cGKI in tumor cells.

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