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Placebo with associated blood transfusion within one hour of injury had an even greater decrease in mortality 14. vs. 0, 1 Patients who received TXA vs.
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Group 1: pills of tranexamic acid 250 mg bid plus placebo gel bid, Tranexamic acid tablets uk 2: pills of placebo bid plus 5% tranexamic acid gel bid and Group 3: pills of placebo bid plus 4% hydroquinone cream at night and a placebo cream at morning. Participants will receive both topical and oral interventions.
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It included 20, 11 patients from 274 hospitals in 40 countries. The CRASH-2 trial was a large randomized placebo-controlled trial that evaluated the efficacy of TXA in patients with trauma14.
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