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User-generated content areas depression patch emsam not depression patch emsam by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. WebMD does not endorse any specific product, service, or treatment. These opinions do not represent the opinions of WebMD. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.

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Selegiline
Clinical data
Pronunciation/ s ə ˈ l ɛ dʒ ɪ l iː n / sə- LEJ -i-leen
Trade namesPill form is generic and available under many brand names; [1] transdermal patch is called Emsam
AHFS/Drugs.comMonograph
MedlinePlusa697046
License dataUS   FDA: Selegiline
Pregnancy categoryAU: B2 US: C (Risk not ruled out)
Routes of administrationOral, transdermal
ATC codeN04BD01 ( WHO ) QN06AX90 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability10% (oral), 73% (patch)
Protein binding94%
MetabolismIn the gut wall and liver
MetabolitesN -desmethylselegiline, L -amphetamine and L -methamphetamine
Elimination half-life10 hours (oral), 18–25 hours (transdermal)
Excretionurine

Although not all of these side effects may occur, if they do occur they may need medical attention. See below for a comprehensive list of emsam maoi effects. Check emsam maoi your doctor immediately if any of the following side effects occur while taking selegiline: Twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs unsteadiness, trembling, or other problems with muscle control or coordination dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position Get emergency help immediately if any of the following symptoms of overdose occur while taking selegiline: severe spasm where the head and heels are bent backward and the body arched emsam maoi side effects of selegiline may occur that emsam maoi do not need medical attention.

These side effects may go away during treatment as your body adjusts to the medicine. Applies to selegiline: oral capsule, oral tablet, oral tablet disintegrating Along with its needed effects, selegiline the active ingredient contained in Emsam may cause some unwanted effects.

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Always check with your doctor or pharmacist before taking any other prescription or over-the-counter medication, depression patch emsam or other supplements while you're taking an MAOI. MAOIs can cause serious reactions when you take them with certain medications, such as other antidepressants, certain pain drugs, certain cold and allergy medications, and some herbal supplements.

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Depression patch emsam ASRs led to dropout in 2% of Emsam-treated patients and no placebo-treated patients. Most ASRs were mild or moderate in severity. Reactions reported by at least 2% of patients treated with Emsam are included, except the following reactions, which had an incidence on placebo treatment greater than or equal to Emsam: infection, nausea, dizziness, pain, abdominal pain, nervousness, back pain, asthenia, anxiety, flu syndrome, accidental injury, somnolence, rhinitis, and palpitations.

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Emsam antidepressant J Psychiatr Res. 2008 Jun. -20. Milad MR, Orr SP, Lasko NB, Chang Y, Emsam antidepressant SL, Pitman RK. Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study.

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  • Although not all of these side effects may occur, if they do occur they may need medical attention. Applies to selegiline: oral capsule, oral tablet, oral tablet disintegrating Along with its needed effects, selegiline (the active ingredient contained in Emsam) may cause some unwanted effects. depression patch emsam
  • Alcohol or marijuana (cannabis) can make you more dizzy emsam maoi drowsy. bipolar disorder, depression, schizophrenia) liver problems, certain nervous system diseases (Parkinson's syndrome, seizures) overactive thyroid (hyperthyroidism) personal or family history of glaucoma (angle-closure type) This drug emsam maoi make you dizzy or drowsy. emsam maoi
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  • 6 There is depression patch emsam evidence that selegiline acts as a neuroprotectant and reduces the rate of disease progression, though this is disputed. 5 Selegiline depression patch emsam the point when levodopa treatment becomes necessary from about 11 months to about 18 months after diagnosis.
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Percent of adults with a past year SUD data not shown receiving substance use treatment in the past year. The percentage of adults emsam maoi treatment emsam maoi alcohol or illicit drug use at a specialty facility was emsam maoi stable over the 13-year period between 2002 and 2014 Figure 5 About 1. percent of the total adult population Figure 5 or 7.

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Depression patch emsam doi. 2001 Nov. -4. ubMed: 1602525Salonen JS, Nyman L, Boobis AR, Edwards RJ, Watts P, Lake BG, Price RJ, Renwick AB, Gomez-Lechon MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Guillouzo A, Depression patch emsam L, Goldfarb PS, Lewis DF, Taavitsainen P, Pelkonen O: Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

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Subsequent development and usage of other FDA-approved MAOIs for depression was accompanied with a number of patients having a hypertensive crisis, with some having strokes. The discovery emsam maoi MAOIs were effective in depression came by serendipity; a MAOI that was an effective antituberculosis drug, iproniazid, helped the depression of a patient with tuberculosis.

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Medline. Ranta K, Tuomisto MT, Kaltiala-Heino R, Rantanen P, Marttunen M. Cognition, Imagery and Coping among Adolescents with Social Anxiety and Phobia: Testing depression patch emsam Clark and Wells Model in the Population. Clin Psychol Psychother. 2013 Jan 24.

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Emsam maoi take different meds for emsam maoi anxiety. The Emsam patch has stopped my depressive episodes that started in Vietnam in 1970 For Depression: I lived in a world of gray with a circle of awareness as little as two feet.

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Emsam maoi should be clear about the limits of the research around that medication and if there are any other options. Off-label means that it hasn t been approved by the Food and Drug Administration for this condition. After starting bupropion, symptoms gradually decrease over emsam maoi period of weeks.

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