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Although antihistamines, including promethazine, have been found to produce fetal mortality in rodents, the pharmacological promethazine dm syrup 240ml of histamine in the rodent do not parallel those in man. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters.

times the maximum recommended total daily dose promethazine dm syrup 240ml promethazine for a 50-kg subject, depending upon the indication for which the drug is prescribed. to 4. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats.

If IV administration of promethazine hydrochloride is required, extreme care should be exercised to avoid extravasation or inadvertent intra-arterial injection. Promethazine should be used with caution, if at all, in patients promethazine dm liq sleep apnea. . Some commercially available formulations of promethazine hydrochloride contain sulfites that may cause allergic-type reactions, including anaphylaxis and life-threatening or less severe asthmatic episodes, in certain susceptible individuals.

The overall promethazine dm liq of sulfite sensitivity in the general population is unknown but probably low; such sensitivity appears to occur more frequently in asthmatic than in nonasthmatic individuals. Because IV administration of the drug has been associated with severe tissue injury, including gangrene requiring amputation, the US Food and Drug Administration FDA states that deep IM injection is the preferred method for administration of promethazine hydrochloride injections.

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DailyMed will deliver this promethazine dm syp morton gro to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. To view updated drug label links, paste the RSS feed address URL shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X. If you no longer wish to have this DailyMed RSS service, simply delete the copied URL from your RSS Reader.

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Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Drugs. Usually avoid combinations; use it only under special circumstances.

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Promethazine dm syrup 240ml Dextromethorphan is metabolized primarily by liver enzymes undergoing O-demethylation, N-demethylation, and partial conjugation with glucuronic acid and sulfate. Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. The duration of action after oral administration is approximately three to six hours.

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0 Promethazine with Promethazine dm syrup coupon Oral Solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older. Contraindicated in pediatric patients 12 to 18 years of age after tonsillectomy or adenoidectomy. f Promethazine with Codeine Oral Solution is used for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be availablesee Warnings and Precautions 5.

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Any combination medicines contain guaifensin. Ask a doctor or pharmacist before using any other cough or cold medicine.

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Because animal reproduction studies are not always predictive of human response, promethazine hydrochloride injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

There are no adequate and well-controlled studies of promethazine hydrochloride injection in pregnant women.

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It is not known whether promethazine HCl or dextromethorphan is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in promethazine dm syrup coupon infants from Promethazine HCl and Dextromethorphan Promethazine dm syrup coupon promethazine and dextromethorphan yrup, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

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