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En general, se debe evitar la administraci n de dosis nicas superiores a 100 mg. Cuando se deba suspender el tratamiento con trazodona, la dosis que toma se reducir de forma gradual. No se debe superar una dosis de 300 mg al d a.

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Adults: 300 mg P. daily. Pharmacodynamics Antidepressant action: Trazodone is thought to exert its antidepressant effects by inhibiting reuptake of trazodone for insomnia mayo clinic and serotonin in CNS nerve terminals presynaptic neurons which enhances activity of these neurotransmitters in the synaptic cleft.

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See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs. Trazodone has the following interaction information: Both trazodone and St John's Wort can increase the risk of serotonin syndrome. ...

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The presence of other medical problems may affect the use of this medicine. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. ...

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