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Ipitor atorvastatin can lower zocor 20 mg para que sirve risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking. t s one of the strongest cholesterol-lowering statin medications. ake your free Depression TestPregnancy CategoriesReturn to contentViews medications by letterLowers bad cholesterol LDL and triglycerides fats and raises good cholesterol HDL in people who have trouble doing this through diet and exercise.

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Because the below reactions are reported voluntarily from a population of uncertain size, it zocor 20 mg para que sirve generally not possible to reliably estimate their frequency or establish a causal relationship to drug exposure. In this trial, patients were carefully monitored and some interacting medicinal products were excluded.

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Other adverse reactions reported in clinical trials were: diarrhea, rash, dyspepsia, flatulence, and asthenia.

Clinical data
Pronunciation/ ˈ s ɪ m v ə s t æ t ɪ n /
Trade namesZocor, other
License dataEU  EMA:  by INN, US   FDA: Simvastatin
Pregnancy categoryAU: D US: X (Contraindicated)
Routes of administrationby mouth
ATC codeC10AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: P (Pharmacy medicines) when ≤10 mg/day, POM when >10 mg/day., US: ℞-only
Pharmacokinetic data
Protein binding95%
MetabolismHepatic (CYP3A4)
Elimination half-life2 hours for simvastatin and 1.9 hours for simvastatin acid
ExcretionRenal 13%, faecal 60%

Chagnon JP, Cerf M "Simvastatin-induced protein-losing enteropathy. Am J Gastroenterol. 257-6439.

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Imetidine, ketoconazole, spironolactone: May increase risk of endocrine dysfunction. Amiodarone, verapamil: Increases risk of myopathy and zocor libido. Don't exceed 20 mg daily for zocor libido dose.

Data sources zocor 20 mg para que sirve IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers. In addition, Zocor raises blood flow to vital organs such as the heart and brain. This blocking of blood bad cholesterol from building up in the arteries and protects against heart You should stay on a cholesterol-lowering diet while taking this medicine.

atty substances called triglycerides in the blood. This material is provided for educational purposes only and is not zocor 20 mg para que sirve for medical advice, diagnosis or treatment.

Zocor alternative name product:
  • Actalipid 10 mg
  • Docsimvasta 5 mg
  • Doctiverine 20 mg
  • Dosavastatin 10 mg
  • Lipex 5 mg
  • Lipinorm 10 mg
  • Lodales 10 mg
  • Normotherin 20 mg
  • Simbastatin 10 mg
  • Simcard 5 mg
  • Simgal 5 mg
  • Simvastatina 10 mg
  • Simvastatinum 40 mg
  • Simvofix 5 mg
  • Simvor 10 mg

Your doctor will determine the appropriate tablet strength for you, depending on your condition, your current treatment and your personal risk status. Do not take Zocor if you are pregnant, zocor 20 mg para que sirve to get pregnant or think you may be pregnant. If you get pregnant while taking Zocor, stop taking it immediately and contact your doctor. Check with your doctor or pharmacist if you are not sure. Do not take Zocor if you are breast-feeding, because it is zocor 20 mg para que sirve known if the medicine is passed into breast milk.

Always take this medicine exactly as your doctor has told you.

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4. and 4. In patients with HoFH, concomitant administration of lomitapide with doses 40 mg Zocor see sections zocor sex drive

Rosuvastatin (Crestor). Simvastatin ( Zocor ). Simvastatin and Ezetimibe (Vytorin). Simvastatin and Niacin (Simcor). Simvastatin and Sitagliptin ...

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Serious liver damage caused by statins is rare. Liver tests should be performed at the beginning of treatment then as zocor 20 mg para que sirve thereafter. Minor side effects include: onstipationDiarrheaFatigueGasHeartburnHeadacheOther commonly reported side effects include: ommon cold nasopharyngitis oint pain arthralgia ain in the extremitiesUrinary tract infectionLipitor may cause liver and muscle damage.

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Do not breast-feed while you are taking this medicine. Take simvastatin exactly as prescribed. Simvastatin may zocor libido into breast milk and could harm a nursing baby.

Liponorm, Medipo, Sinvacor, Sivastin, Zocor. The major aim of statins is to lower the LDL cholesterol level. They reduce LDL cholesterol more than other drugs.: Therapeutic education of patients with coronary ... - CiteSeerX

O-administration of elbasvir and grazoprevir with simvastatin has not been zocor 20 mg para que sirve however, the dose of simvastatin should not exceed 20 mg daily in patients receiving concomitant medication with products containing elbasvir or grazoprevir see section 4. elbasvir and grazoprevir may lead to increased plasma concentrations of simvastatin and an increased risk of myopathy; therefore, a dose adjustment of simvastatin should be considered depending on the prescribed dose.

  • Ww. From FDA website. Accessed 2008 Aug 12.
  • Zocor 20 mg para que sirve Nonalcoholic fatty liver disease or NASH occurs due to the accumulation of abnormal amounts of fat within the liver. Cholesterol management may include lifestyle interventions (diet and exercise) as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range.
  • In patients with severe renal impairment (creatinine clearance 30 ml/min) dosages above 10 mg/day should be carefully considered and, if deemed necessary, implemented cautiously. No modification of dosage should be necessary in patients with moderate renal impairment.
  • 1880-351. Ann Pharmacother.
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant. Use birth control that you can trust to prevent pregnancy while taking Zocor (simvastatin tablets) If you are pregnant or you get pregnant while taking Zocor (simvastatin tablets) call your doctor right away. You could have more zocor 20 mg para que sirve effects.

Consult your doctor for more details. In addition to eating a proper diet such as a zocor sex drive diet other lifestyle changes that may help simvastatin medication work better include exercising, losing weight if overweight, and stopping smoking. This drug maybe used to treat other diseases and conditions. Your doctor may conduct liver function tests when using statins to zocor sex drive liver enzymes and other liver function.

Simvastatin ( Zocor ®). ♢ Simvastatin is a medication used for reducing cholesterol levels in the body. ♢ Its concentration in the body is regulated by SLCO1B1.

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  1. Zocor alternative name: actalipid, docsimvasta, doctiverine, dosavastatin, lipex, lipinorm, lodales, normotherin, simbastatin, simcard, simgal, simvastatina, simvastatinum, simvofix, simvor, sinvacor, sivastin, statinal, vasilip, zeid, zocord, zorced, zorstat, zosta, zostin, zostine, zovast, zovastin, zovatin, zurocid
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Zocor libido elevated simvastatin and simvastatin acid plasma levels which may be due, in part, to interacting drugs that interfere with simvastatin metabolism and/or transporter pathways see section 4. The risk of myopathy is increased by high levels of HMG-CoA reductase inhibitory activity in plasma i. and 4. 4. Simvastatin, like other inhibitors of Zocor libido reductase, occasionally causes myopathy manifested as muscle pain, tenderness zocor libido weakness with creatine kinase CK above ten times the upper limit of normal ULN Myopathy sometimes takes the form of rhabdomyolysis with or without acute renal failure secondary to myoglobinuria, and very rare zocor libido have occurred.

Liverfunction: Liverdisease or reduced liver function may cause this medication to build up in thebody, causing side effects. Kidneyproblems: People withdecreased kidney function should discuss with their doctor how this medicationmay affect their medical condition, how their medical condition may affect thedosing and effectiveness of this medication, and whether any special monitoringis needed. zocor 20 mg para que sirve

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Terms & conditions

Terms and Conditions; Acute overdosage with barbiturates is manifested by CNS and respiratory depression which may progress to Cheyne- Stokes respiration, areflexia, constriction of the pupils to a slight degree though in severe poisoning they may wshow paralytic dilation oliguria, tachycardia, hypotension, lowered body temperature, and coma.

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Marked persistent increases of hepatic transaminases have been noted see Warnings and Precautions 5. In this trial, patients were carefully monitored and some interacting zocor 20 mg para que sirve products were excluded. Elevated alkaline phosphatase and -glutamyl transpeptidase have also been reported. Other adverse reactions reported in clinical trials were: diarrhea, rash, dyspepsia, flatulence, and asthenia.

Does zocor cause low platelets?

The safety profiles were similar between the two treatment groups except that the incidence of myopathy was approximately 1. mmol/L. 1. The absolute difference in LDL-C between the two groups over the course of the study was.

What time of day should i take zocor?

The risk of myopathy and rhabdomyolysis is also increased by concomitant use of amiodarone, amlodipine, verapamil, or diltiazem with certain doses of simvastatin see sections 4. and 4. The risk of myopathy, including rhabdomyolysis, may be increased by concomitant administration of fusidic acid with statins see section 4.

Use of these medicinal products is contraindicated see section 4.

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Arch Intern Med. 1456-730. J Clin Endocrinol Metab. ChoquetKastylevsky G, Kanitakis J, Dumas V, Descotes J, Faure M, Claudy A "Eosinophilic fasciitis and simvastatin. Chan MH, ak TW, hiu RW, how CC, han IH, am CW "Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolaemia.

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After this time, your doctor will likely send you for a bloodtest to check for changes in your cholesterol levels. The medication usuallytakes about 2 to 4 weeks to have a significant effect on the cholesterol levelin your blood.

Can zocor be taken every other day?

Overall, the high-intensity statins atorvastatin and rosuvastatin had the greatest impact on HbA1c. The low-intensity statins pravastatin, fluvastatin and lovastatin had minimal effect on serum glucose. 5 percentage points when taking the drugs.

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"FDA Drug Safety Communication: Revised dose limitation for Zocor simvastatin when taken with amiodarone". U. Food and Drug Administration FDA 15 December 2011 with max safe dose of acetaminophen. Retrieved 3 November 2015.

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Cases of myopathy, including rhabdomyolysis, have been observed with simvastatin coadministered with lipid-modifying doses 1 g/day niacin of niacin-containing products see Drug Interactions 7.

Zocor 20 mg para que sirve benefits of the combined use of simvastatin with the following drugs should be carefully weighed against the potential risks of combinations: other lipid-lowering drugs fibrates or, for patients with HoFH, lomitapide amiodarone, dronedarone, verapamil, diltiazem, amlodipine, or ranolazine see Dosage and Administration 2. Drug Interactions 7.

When did zocor come on the market?

The mean exposure AUC of the main active metabolite, simvastatin acid is 120% in heterozygote carriers CT zocor 20 mg para que sirve the C allele and 221% in homozygote CC carriers relative to that of patients who have the most common genotype TT The C allele has a frequency of 18% in the European population.

In patients with SLCO1B1 polymorphism there is a risk of increased exposure of simvastatin acid, which may lead to an increased risk of rhabdomyolysis see section 4. Based on conventional animal studies regarding pharmacodynamics, repeated dose toxicity, genotoxicity and carcinogenicity, there are no other risks for the patient than may be expected on account of the pharmacological mechanism.

The term dysplasia refers for placement of a PA (2010) Current Views Pseudomonas in particular. Angioedema can occur at any point during treatment with additional reading. The latter is available in tablets of 10 and 20 milligrams each that should be taken 30 to 60 minutes before sexual activity.

21T C allele have lower OATP1B1 activity.

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Elevated plasma levels of HMG-CoA reductase inhibitory activity increases the risk of myopathy and rhabdomyolysis, particularly with higher doses of simvastatin. Simvastatin is metabolized by CYP3A4 but has no CYP3A4 inhibitory activity; therefore it is not expected to affect the plasma concentrations of other drugs metabolized by CYP3A4.

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European Heart Journal. the evidence focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.

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South Med J. 318-2022. Diaczok BJ, hali R "Statins unmasking a mitochondrial myopathy: a case report and proposed mechanism of disease.

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