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82 Due to metformin's low molecular weight and lack of plasma protein binding, these techniques have the benefit of removing metformin from blood plasma, preventing further lactate overproduction. 79 The most common symptoms following overdose include vomiting, diarrhea, abdominal pain, tachycardia, drowsiness, and, rarely, hypoglycemia or hyperglycemia.

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"Some reports indicate that metformin is associated with preferential fat loss, and it may impart mild anorexic effects via its hypothalamic actions. Haleigh A. James, M. an endocrine trainee in Endocrinology, Diabetes, Metabolism Nutrition at Mayo Clinic's campus in Minnesota, notes: "One of its major advantages is that metformin does not cause significant hypoglycemia.

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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers. Talk to your healthcare provider about how to prevent, recognize, and take care of low blood sugar hypoglycemia high blood sugar hyperglycemia and problems you have because of your diabetes.

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