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Consult your doctor for more details and to discuss the use of reliable forms of birth control (such as condoms, birth control pills) while taking this medication. Atorvastatin (atorlip-10) pkge. 10 mg 30 package quantity.

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Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Cholesterol and triglycerides can clog your blood vessels. It is especially important to lower your cholesterol if you have heart disease, smoke, have diabetes or high blood pressure, are older, or if heart disease starts early in your family. Some atorvastatin calcium tablets 20 mg should not be taken with Atorvastatin Calcium Tablets.

Should be taken into account for the paediatric population. The above mentioned interactions for adults and the warnings in section 4.

Adverse Reactions 6. Clinical Pharmacology 12. and Clinical Studies 14. The safety and effectiveness of LIPITOR atorvastatin calcium tablets 20mg been established in pediatric patients, 10 years to 17 years of age, with HeFH as an adjunct to diet to reduce total cholesterol, LDL-C, and apo B levels when, after an adequate trial of diet therapy, the following are present: Use of LIPITOR for this indication is supported by evidence from see Dosage and Administration 2.

The LDL cholesterol reductions seen by atorvastatin dose were 37% at 10 mg ( mean baseline LDL-C 185 mg/dL), 42% at 20 mg (mean baseline ...: Liptruzet (ezetimibe and atorvastatin) - CenterWatch

There have been rare reports of congenital anomalies following intrauterine exposure to statins. There atorvastatin calcium tablets 20 mg no adequate and well-controlled studies of atorvastatin use during pregnancy.

Exceptional cases of interstitial lung disease, especially with long term therapy see section 4. It allows continued monitoring of the benefit/risk balance of the medicinal product. Based on the data available, the frequency, type atorvastatin calcium tablets 20mg severity of adverse reactions in children is similar to adults.

Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at hra. mmol/L, BMI 30kg/m2, raised triglycerides, history of hypertension Reporting suspected adverse reactions after authorisation of the medicinal product is important. Diabetes Mellitus: Frequency atorvastatin calcium tablets 20mg depend on the presence or absence of risk factors fasting blood glucose 5.

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Treat patient symptomatically, and provide supportive measures as required. Withhold or discontinue drug in patients with serious, acute conditions that suggest myopathy or those at risk for renal failure secondary to rhabdomyolysis as a result of trauma; major surgery; severe metabolic, endocrine, and electrolyte disorders; severe acute infection; hypotension; or uncontrolled seizures.

Special considerations Before starting drug, exclude secondary causes of hypercholesterolemia and perform a baseline lipid profile. There's no specific treatment for overdose. Because of extensive drug binding to plasma proteins, hemodialysis isn't expected to significantly enhance drug clearance. Obtain periodic liver function tests and lipid levels before starting treatment, at 6 and 12 weeks after treatment starts, or after an increase in dosage and periodically thereafter. atorvastatin calcium 20 mg tab apot

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Symptoms of fatty liver disease are primarily the complications of cirrhosis of the liver; and may include mental changes, liver cancer, the accumulation of fluid in the body para que sirve atorvastatin calcium 20 mg, edema and gastrointestinal bleeding. Getting your cholesterol and triglyceride levels in an optimal range will help protect your heart and blood vessels.

Cholesterol management may include lifestyle interventions diet and exercise as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range.

Nonalcoholic fatty liver disease or NASH occurs due to the accumulation of abnormal amounts of fat within the liver. Fatty liver most likely caused by obesity and diabetes.

RESEARCH DONE IN USA CARDIOVASCULAR DISEASE ...; P.C. Deedwania, M. Gupta, M. Stein, J. Ycas, and A. Gold, Comparison of rosuvastatin versus atorvastatin in. South-Asian patients at risk of coronary heart  ...

Atorvastatin calcium 20 mg tab apot A person has traditionally been That ideal weight must take into account the person's height, age, sex, and High blood pressure hypertension means high pressure tension in the arteries. Treatment for high blood pressure include lifestyle modifications alcohol, smoking, coffee, salt, diet, exercise drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers CCBs alpha blockers, clonidine, minoxidil, and Exforge.

EFERENCE: CDC. High Blood Pressure. Updated: Nov. Obesity is the state of being well above one's normal weight. threatening diseases like stroke and heart attack.

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Your doctor may do further tests to diagnose the cause of your muscle problems. allergic reactions including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing which may require treatment right away.

muscle problems that do not go away even after your doctor has advised you to stop taking atorvastatin calcium tablets. This may be an early sign of a rare muscle problem.

Atorvastatin calcium tablets 20 mg For dosage recommendations for amlodipine, he maximum dosage of atorvastatin or amlodipine in the fixed-combination preparation is 80 or 10 mg daily, respectively.

The ACC/AHA cholesterol management guideline states that decreasing the statin dosage in adults may be considered when LDL-cholesterol concentrations are less than 40 mg/dL on 2 consecutive measurements; however, there are no data to suggest that LDL-cholesterol concentrations below 40 mg/dL would increase the risk of adverse effects.

Doses of amlodipine and atorvastatin should be selected independently.

June. 9, P. EMEA) FDA Drug Safety Communication: New restrictions, contraindications, and dose limitations for Zocor (simvastatin) to atorvastatin calcium 20 mg tab apot the risk of muscle injury. Early symptoms of myopathy include muscle pain, weakness or tenderness, and dark urine. There have been rare postmarketing reports of cognitive impairment (e. There have been rare reports of immune-mediated necrotizing myopathy associated with statin usesee Warnings and Precautions (5.
Atorvastatin calcium tablets 20 mg Atherosclerosis is a chronic process, and ordinarily discontinuation of lipid-lowering medicinal products during pregnancy should have little impact on the long-term risk associated with primary hypercholesterolaemia. Maternal treatment with atorvastatin may reduce the fetal levels of mevalonate which is a precursor of cholesterol biosynthesis. Myopathy should be considered in any patient with atorvastatin calcium tablets 20 mg myalgias, muscle tenderness or weakness, and/or marked elevation of CPK. Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever or if muscle signs and symptoms persist after discontinuing atorvastatin. What is atorvastatin calcium 20 mg A chemically similar drug in this class produced optic nerve degeneration (Wallerian degeneration of retinogeniculate fibers) in clinically normal dogs in a dose-dependent fashion at a dose that produced plasma drug levels about 30 times higher than the mean drug level in humans taking the highest recommended dose.
Atorvastatin calcium tablets 20mg Atorvastatin, like other statins, occasionally causes myopathy, defined as muscle aches or muscle weakness in conjunction with increases in creatine phosphokinase (CPK) values 10 times ULN. The concomitant use of higher doses of Atorvastatin with certain drugs such as cyclosporine and strong cytochrome P450 3A4 (CYP3A4) inhibitors (e. Such patients merit closer monitoring for skeletal muscle effects. atorvastatin calcium tablets 20mg Atorvastatin calcium tablets 20mg cbi. Patients taking digoxin should be monitored appropriately. When multiple doses of Atorvastatin and digoxin were co-administered, atorvastatin calcium tablets 20mg state plasma digoxin concentrations increased see Clinical Pharmacology (12.

Atorvastatin calcium tablets 20mg

Ederberg, H. et al. Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of atorvastatin calcium tablets 20mg METSIM cohort. Lancet 6.

The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Selected from data included with permission and copyrighted by First Databank, Inc.

This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise atorvastatin calcium tablets 20mg judgment of healthcare professionals.

insberg HN, Elam MB, Lovato LC, Crouse JRetal. Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med atorvastatin calcium tablets 20mg Apr. 1563-74.

Atorvastatin properties
Drug name Atorvastatin
Atorvastatin synonyms
Active substanceatorlip-10
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The prognosis of a patient with congestive heart failure depends on the stage of the heart failure and the overall condition of the A stroke is an interruption of the blood supply to part of the brain caused by either a blood clot ischemic or bleeding hemorrhagic Symptoms of a stroke may include: weakness, numbness, double vision or vision loss, confusion, vertigo, difficulty speaking or understanding speech.

Treatment of heart failure consists of lifestyle modification and taking medications to decrease fluid in the body and ease the atorvastatin calcium 20 mg tab apot on the heart. A physical exam, imaging tests, neurological exam, and blood tests may be used to diagnose a stroke.

Physical examination, atorvastatin calcium 20 mg tab apot history, blood tests, and imaging tests are used to diagnose congestive heart failure.

Current medications are: atorvastatin 20 mg daily, hydrochlorothiazide 25 mg daily. BP is 154/92 mm Hg, HR 80 bpm. SCr 1.2 mg/dL (eGFR 73 mL/min/1.73 m2), ...: Controversial High Impact Publications in Hypertension - ASHP

Data from comparative studies indicate that therapy with atorvastatin may produce greater reductions in total and LDL-cholesterol concentrations than certain other statins. Increases in HDL-cholesterol concentrations also have atorvastatin calcium tablets 20mg observed in other studies in patients with primary hypercholesterolemia or mixed dyslipidemia; pooled data from 24 controlled studies indicate median increases of 5-9% in HDL-cholesterol concentrations in patients receiving atorvastatin 10-80 mg daily.

Analysis of pooled data demonstrated consistent and substantial decreases in total cholesterol, LDL-cholesterol, triglyceride, total-cholesterol/HDL-cholesterol ratio, and LDL-cholesterol/HDL-cholesterol ratio in patients receiving atorvastatin. In patients with dyslipidemia and hypertension who received atorvastatin 10-80 mg daily in atorvastatin calcium tablets 20mg with amlodipine 5-10 mg daily LDL-cholesterol concentrations were reduced by 36-48% following 8 weeks of therapy.

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Help center, 7 Number of orphan drugs in clinical trials: 600 7 Number of orphan drugs in Phase-2 Trial: 231 7 Number of orphan drugs in U.

clinical trials: 350 in the pipeline from research until registration 7 According to Thomson Reuters in their 2012 publication "The Economic Power of Orphan Drugs, there has been increased investment in orphan drug research and development, partly due to the U.

S. Orphan Drug Act of 1983 ODA and similar acts in other regions of the world driven by "high-profile philanthropic funding. Cancer treatment was the indication in more than 30% of orphan drug trials.

Which is stronger atorvastatin or rosuvastatin?

Consider therapy modification Grazoprevir: May increase the serum concentration of AtorvaSTATin. Management: Limit the dose of atorvastatin to a maximum of 20 mg/day when used together with elbasvir and grazoprevir.

onsider using a lower statin dose or a statin that is less likely to interact when possible. Avoid high quantities of GFJ with atorvastatin.

Is atorvastatin 10 mg tablet a substitute for plavix?

The extent of interactions in the paediatric population is not known. Drug-drug interaction studies have only been performed in adults.

Does atorvastatin affect gout?

After completing the atorvastatin calcium tablets 20mg study, eligible patients were assigned to coadministered ezetimibe atorvastatin calcium tablets 20mg atorvastatin equivalent to Http:// 10/10-10/80 or atorvastatin 10-80 mg/day for an additional 48 weeks.

The most common adverse reactions in the group treated with LIPTRUZET that led to treatment discontinuation and occurred at a rate greater than placebo were: The most commonly reported adverse reactions incidence 2% and greater than placebo in this trial were: increased ALT 5% increased AST 4% and musculoskeletal pain 4% LIPTRUZET has been evaluated for safety in 2403 patients in 7 clinical trials one placebo-controlled trial and six active-controlled trials Table 2*: Clinical and Selected Laboratory Adverse Reactions Occurring in 2% of Patients Treated with LIPTRUZET and at an Incidence Greater than Placebo, Regardless of Causality Placebo-controlled combination study atorvastatin calcium tablets 20mg which the active ingredients equivalent to LIPTRUZET were coadministered.

Can atorvastatin cause false positive?

If this doesn t help, talk to your pharmacist or doctor. onstipation or wind - eat more high-fibre foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise more regularly, for example, by going for a daily walk or run.

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Limited evidence indicates that treatment with atorvastatin also may slow the progression of atherosclerosis in these patients. Patients with homozygous familial hypercholesterolemia usually respond poorly to combined dietary management and drug therapy, including regimens containing a statin, in part because these patients have poorly functioning, few, or no LDL receptors.

In an uncontrolled study in 29 patients 6-37 years of age with homozygous familial hypercholesterolemia, LDL-cholesterol concentrations were reduced by 7-53% mean reduction of 20% in 25 of 29 patients 86% and increased by 7-24% in 4 of 29 patients 14% who received atorvastatin dosages of 20-80 mg daily; 5 of the 29 patients had absent LDL-receptor function of these, 2 patients also had a portacaval shunt and had no substantial reduction in LDL-cholesterol concentrations, and the remaining 3 receptor-negative patients had a mean LDL-cholesterol reduction of 22% Similar reductions 17-28% were observed in another open-label study in which patients received atorvastatin dosages of 40-80 mg daily for at least 4 weeks.

In a limited number of patients undergoing plasma LDL-apheresis to lower cholesterol concentrations, addition atorvastatin calcium 20 mg tab apot atorvastatin 80 mg daily for 8 atorvastatin calcium 20 mg tab apot reduced plasma total and LDL-cholesterol concentrations by an additional 29 and 31% respectively.

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If you miss a dose of Atorvastatin calcium tablets, take it as soon as you remember. If you take atorvastatin calcium tablets 20 mg much Atorvastatin calcium tablets or overdose, call your doctor or Poison Control Center right away.

Stay on this low-fat diet when you take Atorvastatin calcium tablets. Do not take two doses of Atorvastatin calcium at the same time. Do not take Atorvastatin calcium tablets if it has been more than 12 hours since you missed your last dose. Wait and take the next atorvastatin calcium tablets 20 mg at your regular time.

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The dose of saquinavir plus ritonavir in this study is not the clinically used dose. However, atorvastatin calcium tablets 20mg inhibitors of CYP3A e. itraconazole, clarithromycin may increase the atorvastatin calcium tablets 20mg concentrations of amlodipine to a greater extentsee DRUG Greater increases in AUC up to 2. -fold and/or Cmax up to 71% have been co-administration of atorvastatin with rifampin is recommended, as delayed administration of atorvastatin after administration of rifampin has been associated with a significant reduction in atorvastatin plasma concentrations.

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Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention. poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide symptoms of high blood sugar e.

Check with your doctor as soon as possible if any of the following side effects occur: signs of depression e. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. atorvastatin calcium 20 mg tab apot

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When taking atorvastatin, you need to abstain from eating grapefruit or drinking grapefruit juice, as these may boost levels of the drug to hazardous intensities in your system. Runny or Stuffy Nose, Sneezing, Coughing, Sore or Scratchy Throat nasopharyngitis Excessive alcohol consumption can boost triglyceride levels and may cause harm to the liver; conserve your health by drinking in moderation when taking Lipitor.

There atorvastatin calcium tablets 20 mg numerous medications that interact with atorvastatin, including: HIV medications such as darunavir, fosamprenavir, ritonavir, and various others Medicines that contain niacin for example Advicor, Niaspan, Niacor, and various others Drugs that atorvastatin calcium tablets 20 mg your immune system such as steroids, cancer medicine and others Medicines atorvastatin calcium tablets 20 mg to prevent organ transplant rejection such as sirolimus, tacrolimus and others Here is some information that may be of interest to anyone on a Lipitor regimen or discussing taking Lipitor with a health care provider: Individuals often ask about Lipitor in connection with weight gain.

In addition, when taking atorvastatin, older adults and individuals who have kidney disease or poorly controlled hypothyroidism underactive thyroid may have complications that can produce a failure of skeletal muscle tissue, leading to a breakdown in kidney function. The same goes for excess alcohol consumption, for alcohol can cause injury to the liver and raise triglyceride levels.

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For patients with Heterozygous Familial Hypercholesterolemia aged atorvastatin calcium tablets 20 mg years and above, the recommended starting dose of atorvastatin is 10 mg per day see section 5 or high calcium beans.

Efficacy and safety in patients older than 70 using recommended doses are similar to those seen in the general population. Paediatric use should only be carried out by physicians experienced in the treatment of paediatric hyperlipidaemia and patients should be re-evaluated on a regular basis to assess progress. atorvastatin calcium tablets 20 mg

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The risk of this occurring is increased when taking certain types of medication or consuming larger quantities 1 liter of grapefruit juice. Patients should also be advised to inform other healthcare professionals prescribing a new medication that they are taking atorvastatin calcium tablets.

All patients starting therapy with atorvastatin calcium tablets should be advised of the risk of myopathy and told to report promptly any unexplained muscle pain, tenderness, or weakness particularly if accompanied by malaise or fever or if these muscle signs or symptoms persist after discontinuing atorvastatin calcium.

Atorvastatin calcium tablets are supplied as white, oval, biconvex film-coated tablets of atorvastatin calcium containing 40 mg atorvastatin. Patients should be advised about substances they should not take concomitantly with atorvastatin see Warnings and Precautions 5. para que sirve atorvastatin calcium 20 mg

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Remember to take it at the same time each day. ake this medication regularly in order to get the most benefit from it. f you also take certain other drugs to lower your cholesterol bile acid-binding resins such as cholestyramine or colestipol take atorvastatin at least 1 hour before or at least 4 hours after taking these medications. These products can react with atorvastatin, preventing its full absorption. para que sirve atorvastatin calcium 20 mg

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What is atorvastatin calcium 20 mg Trans-fats are found in many brands of margarine and in most heavily processed foods, such as chips, crackers and cookies, and in the oils used to cook fast-food French fries, doughnuts and movie popcorn. Emotional stress may prompt the body to release fat into the bloodstream, raising cholesterol levels. These heart-damaging fats can reduce HDL good cholesterol levels and raise levels of LDL cholesterol.

Avoid trans-fatty acids.

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